In 2001 Kerzner teamed up with IK Multimedia to offer the sounds he created for keyboard workstations via computer software. Kerzner's sounds have been used by artists worldwide. Sonic Reality also produces 'play along' DrummerTracks and other backing tracks for guitarists, bass players, keyboardists, and singers to work with via various audio devices, mobile devices, and recording software. The sounds are played from music software such as samplers and other music recording tools. While developing music technology and creative tools for musicians, Kerzner collaborated with professional artists to sample and digitally reproduce the sounds of many types of musical instruments. In 1996 Kerzner founded the sound development company Sonic Reality Inc, which focuses on the sampling of every type of musical instrument from vintage keyboards to drums to orchestral and world instruments. In 2010 Kerzner contributed sound design and assistance with music software for Steven Wilson's album Grace For Drowning.

Between 20, Kerzner collaborated musically with Simon Collins. In 2005 Kerzner performed with Jon Anderson of Yes along with Nick D'Virgilio, Stan Cotey, and Mark Hornsby under the band name Sonik Elementz for a one-off performance of ' Long Distance Runaround' during the Winter NAMM convention in Anaheim, California. Kerzner joined the band Giraffe as keyboardist for a one-off tribute performance of Genesis' The Lamb Lies Down on Broadway album at Progfest '94 in Los Angeles. In 1994, Kerzner contributed to Kevin Gilbert's solo album, Thud and appeared as a band member on Gilbert's live album Live at the Troubadour. Following this endeavor into the music software industry, Kerzner worked with such recording artists as Madonna, Ringo Starr, and Moog Cookbook as both a musician and as a sound engineer. When 16-bit stereo digital sampling technology became available, Kerzner sampled these instruments to license to such major digital musical instrument manufacturers as Alesis, Roland and Yamaha. In the early 1990s, Kerzner began collecting rare musical instruments. The early years were spent tirelessly working/developing original recordings, along with Dave Silverman (bass and vocals). Dave Kerzner's interest in progressive music was born upon his exposure to early Genesis, as introduced to him by his good friend and band collaborator Jamie Rickel (drums).

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